Hormones & markers · In plain English

SHBG (sex hormone-binding globulin)

A protein made by the liver that carries hormones, including testosterone, in the blood.

Also searched as: sex hormone binding globulin

Why you might see this term

SHBG helps put a total testosterone value in context because changes in binding proteins affect how much hormone is available to tissues.

What to keep in mind

It is not a direct fertility measure. Medicines, thyroid function and other health factors can influence the level.

Sources & further reading

Prepared by ProFertility · Updated 23 October 2026.

Educational information based on the linked sources. This explanation is not an individual diagnosis or a treatment recommendation. A term appearing here does not mean the test is necessary or included in a particular kit.

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